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The photoswitching rates of fluorescent dyes are as unique as a fingerprint and as readable as a barcode.

Researchers at the University of Würzburg develop the "photoswitching fingerprint analysis". A unique technology that for the first time allows the analysis of molecular processes and revolutionises biomedical research.

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Smallpox viruses - here seen under the microscope - are among the deadliest pathogens in human history. Not quite as dangerous, but still worrying, is the current outbreak of monkeypox.

Poxviruses pose a threat to humanity that should be taken seriously, as the current outbreak of monkeypox shows. A research team from the University of Würzburg is now working on the development of new drugs.

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On the left, a stained adenocarcinoma from the lung. The enlarged section B shows healthy lung tissue, the enlarged section C an adenocarcinoma. Section D shows the PET-CT of a metabolically active central lung tumour, close to the trachea, heart and oesophagus. The irradiation dose distribution is shown in colour: Desired dose 100% in the tumour and 80% in the extended tumour area. 25% and 10% of the irradiation dose (turquoise and blue lines) in the healthy tissue for technical reasons.

Some lung tumours do not respond to radiation therapy. This effect can be reversed by blocking an enzyme in the tumour cells, as Würzburg researchers report.

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Jörg Vogel and Linda Popella are redsearching a new class of antibiotics.

Similar to the vaccines against the coronavirus, RNA-based antibiotics could significantly improve modern medicine. Research teams from Würzburg have investigated the prerequisites that such antibiotics must meet for this strategy to work.

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Picture showing a server farm

The Faculty of Law at the University of Würzburg offers the new Master's program "Digitalization and Law". The courses are taught in English.

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Alumna Hina Ghafoor lived and researched in Würzburg for almost six years. Refugees and their situation were a focus of her research.

After her time at the University of Würzburg, alumna Hina Ghafoor went back to Pakistan. There she is investigating cultural differences, for example in dealing with psychosocial stress.

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The thymus, a small lymphatic organ, is located behind the breastbone. As we age, it shrinks considerably with the result that the immune defence becomes weaker.

In old age, the performance of the immune system decreases, and older people are more susceptible to infections. Research teams from Würzburg and Freiburg have now discovered an approach that could be used to slow down this process.

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Organoid-based models: bladder organoids

The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg. Dr. Carmen Aguilar will use this grant to search for new therapeutic approaches against one of the most common and recurrent bacterial infections.

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Image of patient-derived endocervical columnar (red) ectocervical stratified squamous organoids (Green) of female reproductive tract, and diagram depicting their genetic manipulation and infections.

Life-like organ replicas - so-called 3D organoids - are a good way to research disease processes. A team from the University of Würzburg has now presented a kind of blueprint for such a model of the cervix.

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This is the first image of Sagittarius A*, the supermassive black hole at the centre of our galaxy. It shows glowing gas orbiting around the black hole, revealing a telltale signature: a dark central region (called a “shadow”) surrounded by a bright ring-like structure. The new view captures light bent by the powerful gravity of the black hole.

Astronomers have unveiled the first image of the supermassive black hole at the centre of our own Milky Way galaxy. Astronomers of the University of Würzburg were part of this collaboration.

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Photos of the grasshopper species Gravel Grasshopper, Green Mountain Grasshopper, and the Wart-biter.

Little is known about the food webs of herbivorous insects. A team from the Würzburg Biocenter is investigating, in Lower Franconia as well as in the Berchtesgaden Alps.

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Vegan spaghetti is ideally responsible for 130 grams of CO2 emissions. The variant with minced meat sauce is significantly higher.

If restaurants list the CO2 emissions for each dish on their menus or highlight low-emission options, diners are more likely to choose more climate-friendly options. This has been shown in a new study by the University of Würzburg.

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