Sonderforschungsbereich 688 (2006 - 2017)

    Publikationen 2013




    1. Aranguren, X.L., Beerens, M., Coppiello, G., Wiese, C., Vandersmissen, I., Lo Nigro, A., Verfaillie, C.M., Gessler, M., and Luttun, A. (2013). COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1. J Cell Sci 126: 1164-1175. PubMed: 23345397 (TP A16)
    2. Bender, M., May, F., Lorenz, V., Thielmann, I., Hagedorn, I., Finney, B.A., Vogtle, T., Remer, K., Braun, A., Bosl, M., et al. (2013). Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice. Arterioscler Thromb Vasc Biol 33: 926-934. PubMed: 23448972 (TP A01)
    3. Bezzina C.R., Barc J., Mizusawa Y., Remme C.A., Gourraud J.B., Simonet F., Verkerk A.O., Schwartz P.J., Crotti L., Dagradi F., et al. (2013). Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet 45: 1044-1049. PubMed: 23872634 (TP A16)
    4. Bittner S., Ruck T., Schuhmann M.K., Herrmann A.M., Maati H.M., Bobak N., Göbel K., Langhauser F., Stegner D., Ehling P., et al. (2013). Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nat Med. PubMed: 23933981 (TP A13)
    5. Deppermann C., Cherpokova D., Nurden P., Schulz J.N., Thielmann I., Kraft P., Vögtle T., Kleinschnitz C., Dütting S., Krohne G., et al. (2013). Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice. J Clin Invest 123:3331–42. PubMed: 23863626 (TP B01, A01)
    6. Frantz, S., Hofmann, U., Fraccarollo, D., Schafer, A., Kranepuhl, S., Hagedorn, I., Nieswandt, B., Nahrendorf, M., Wagner, H., Bayer, B., et al. (2013a). Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction. FASEB J 27: 871-881. PubMed: 23159933 (TP A10, A01, Z02)
    7. Frantz, S., Klaiber, M., Baba, H.A., Oberwinkler, H., Volker, K., Gabetaner, B., Bayer, B., Abebetaer, M., Schuh, K., Feil, R., et al. (2013b). Stress-dependent dilated cardiomyopathy in mice with cardiomyocyte-restricted inactivation of cyclic GMP-dependent protein kinase I. Eur Heart J 34: 1233-1244. PubMed: 22199120 (TP A07, A10)
    8. Frey A, Ertl G, Angermann CE, Hofmann U, Störk S, Frantz S. Complement C3c as a Biomarker in Heart Failure. Mediators of Inflammation, Vol. 2013, Article ID 716902, 7 pages, 2013 PMID: 24489446 (TP A10)
    9. Kampf T., Helluy X., Gutjahr F.T., Winter P., Meyer C.B., Jakob P.M., Bauer W.R., and Ziener C.H. (2013) Myocardial perfusion quantification using the T1 -based FAIR-ASL method: The influence of heart anatomy, cardiopulmonary blood flow and look-locker readout. Magn Reson Med. PubMed 23836533 (TP B05)
    10. Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Gobel, K., Schuhmann, M.K., Langhauser, F., Helluy, X., Schwarz, T., Bittner, S., et al. (2013). Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood 121: 679-691. PubMed: 23160472 (TP A13, A12, A01, B01)
    11. Kraft P, Göb E, Schuhmann MK, Göbel K, Deppermann C, Thielmann I, Herrmann AM, Lorenz K, Brede M, Stoll G, Meuth SG, Nieswandt B, Pfeilschifter W, Kleinschnitz C. 2013. FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection. Stroke 44(11):3202-10. doi: 10.1161/STROKEAHA.113.002880. PMID: 24029635 (TP A13)
    12. Li X., Bauer W., Kreissl M.C., Weirather J., Bauer E., Israel I., Richter D., Riehl G., Buck A., and Samnick S. (2013). Specific somatostatin receptor II expression in arterial plaque: (68)Ga-DOTATATE autoradiographic, immunohistochemical and flow cytometric studies in apoE-deficient mice. Atherosclerosis 230: 33-39. PubMed: 23958249 (TP Z02)
    13. Manthey HD, Cochain C, Barnsteiner S, Karshovska E, Pelisek J, Koch M, Chaudhari SM, Busch M, Eckstein HH, Weber C, Koenen RR, Zernecke A. CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. Thromb Haemost. 2013 Dec;110(6):1267-77. PMID: 24114205 (TP A22)
    14. Mischnik M, Boyanova D, Hubertus K, Geiger J, Philippi N, Dittrich M, Wangorsch G, Timmer J, Dandekar T. A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation. Mol Biosyst. 2013 Jun;9(6):1326-39. PubMed: 23463387 (TP A02)
    15. Morowski, M., Vogtle, T., Kraft, P., Kleinschnitz, C., Stoll, G., and Nieswandt, B. (2013). Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice. Blood 121: 4938-4947. PubMed: 23584880 (TP B01, A01)
    16. Richter D., Basse-Lüsebrink T.C., Kampf T., Fischer A., Israel I., Schneider M., Jakob P.M., and Samnick S. (2013). Compressed sensing for reduction of noise and artefacts in direct PET image reconstruction. Z Med Phys. PubMed: 23756331 (TP Z02)
    17. Ruppert, C., Deiss, K., Herrmann, S., Vidal, M., Oezkur, M., Gorski, A., Weidemann, F., Lohse, M.J., and Lorenz, K. (2013). Interference with ERKThr188 phosphorylation impairs pathological but not physiological cardiac hypertrophy. Proc Natl Acad Sci U S A 110: 7440-7445. PubMed: 23589880 (TP A17)
    18. Stegner D., Thielmann I., Kraft P., Frohman M.A., Stoll G., and Nieswandt B. (2013a). Pharmacological inhibition of phospholipase d protects mice from occlusive thrombus formation and ischemic stroke--brief report. Arterioscler Thromb Vasc Biol 33: 2212-2217. PubMed: 23868933 (TP B01)
    19. Stegner, D., Deppermann, C., Kraft, P., Morowski, M., Kleinschnitz, C., Stoll, G., and Nieswandt, B. (2013). Munc13-4 mediated secretion is essential for infarct progression but not intracranial haemostasis in acute stroke. J Thromb Haemost 11: 1430-1433. PubMed: 23659589 (TP B01, A01)


    1. Seifried, A., Schultz, J., and Gohla, A. (2013). Human HAD phosphatases: structure, mechanism, and roles in health and disease. FEBS J 280: 549-571. PubMed: 22607316 (TP A11)