Sonderforschungsbereich 688 (2006-2017)

    Publikationen 2008



    1. Adamson RH, Ly JC, Sarai RK, Lenz JF, Altangerel A, Drenckhahn D, Curry FE (2008) Epac/Rap 1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery. Am J Physiol Heart Circ Physiol 294:H1188-1196 (A04) Pubmed:18178724
    2. Baumer Y, Burger S, Curry FE, Golenhofen N, Drenckhahn D, Waschke J (2008) Different role of Rho GTPases in endothelial barrier regulation dependent on endothelial cell origin. Histochem Cell Biol 129:179-191 (A04) Pubmed:18030489
    3. Baumer Y, Drenckhahn D, Waschke J (2008) cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium. Histochem Cell Biol 129:765-778 (A04) Pubmed:18392843
    4. Benz PM, Blume C, Moebius J, Oschatz C, Schuh K, Sickmann A, Walter U, Feller SM, Renné T (2008) Cortical actin cytoskeletons are assembled by protein kinase A-regulated αII-spectrin/VASP complexes. J Cell Biol 180:205-219 (N01, A03, A02) Pubmed:18195108
    5. Benz PM, Blume C, Moebius J, Oschatz C, Schuh K, Sickmann A, Walter U, Feller SM, Renné T (2008) Cytoskeleton assembly at endothelial cell-cell contacts is regulated by αII-spectrin-VASP complexes. J Cell Biol 180:205-219 (N01,A02;A03) Pubmed:18195108
    6. Benz PM, Feller SM, Sickmann A, Walter U, Renné T (2008) Prostaglandin-induced VASP phosphorylation controls αII-spectrin breakdown in apoptotic cells. Int Immunopharmacol 8:319-324 (N01,A02;A03) Pubmed:18182247
    7. Birschmann I, Mietner S, Dittrich M, Pfrang J, Dandekar T, Walter U (2008) Use of functional highly purified human platelets for the identification of new proteins of the IPP signaling pathway. Thromb Res 122:59-68 (A02) Pubmed:17931695
    8. Blecharz K, Drenckhahn D, Förster C (2008) Glucocorticoids increase VE-cadherin expression and cause cytoskeletal re-arrangements in murine brain endothelial cEND cells. J Cereb Blood Flow Metab 28:1139-1149 (A05) Pubmed:18231113
    9. Blenk S, Engelmann JC, Pinkert S, Weniger M, Schultz J, Rosenwald A, Muller-Hermelink HK, Muller T, Dandekar T (2008) Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer 8:106 (A02) Pubmed:18416826
    10. Dittrich M, Birschmann I, Mietner S, Sickmann A, Walter U, Dandekar T (2008) Platelet protein interactions: map, signaling components, and phosphorylation groundstate. Arterioscler Thromb Vasc Biol 28:1326-1331 (A02) Pubmed:18451328
    11. Dittrich MT, Klau GW, Rosenwald A, Dandekar T, Muller T (2008) Identifying functional modules in protein-protein interaction networks: an integrated exact approach. Bioinformatics 24:i223-231 (A02) Pubmed:18586718
    12. Förster C, Burek M, Romero IA, Weksler B, Couraud PO, Drenckhahn D (2008) Glucocorticoids and TNF-α act differently on brain endothelial tight junction proteins in an in vitro model of human Blood-Brain Barrier. J Physiol 586:1937-1949 (A05) Pubmed:18258663
    13. Frantz S, Hu K, Adamek A, Wolf, J, Sallam, A, Maier SK, Lonning S, Ling H, Ertl G, Bauersachs J (2008) Transforming growth factor-ß inhibition increases mortality and left ventricular dilatation after myocardial infarction. Basic Res Cardiol 103:485-492 (A10) Pubmed:18651091
    14. Gambaryan S, Kobsar A, Hartmann S, Birschmann I, Kuhlencordt PJ, Muller-Esterl W, Lohmann SM, Walter U (2008) NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity. J Thromb Haemost 6:1376-1384 (A02) Pubmed:18485089
    15. Harke N, Leers J, Kietz S, Drenckhahn D, Förster C (2008) Identification of a distal glucocorticoid responsive element in the occludin gene coding region. Mol Cell Endocrinol 295:39-47 (A05) Pubmed:18782596
    16. Hartmann M, Skryabin BV, Müller T, Gazinski A, Schröter J, Gaßner B, Nikolaev VO, Bünemann M, Kuhn M (2008) Alternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signalling. J Biol Chem 283:28313-28320 (A07;B06) Pubmed:18713751
    17. Kleinschnitz C, Bräuninger S, Pham M, Nölte I, Renné T, Nieswandt B, Bendszus M, Stoll G (2008) Blocking of Platelets and the Intrinsic Coagulation Pathway Does Not Prevent Cerebral Infarctions Induced by Photothrombosis. Stroke 39:1262-1268 (A03;A01;B01) Pubmed:18292385
    18. Müller-Marschhausen K*, Waschke J, Drenckhahn D (2008) Physiological hydrostatic pressure protects endothelial monolayer integrity in vitro. Am J Physiol Cell Physiol 294:C324-332 (A04) Pubmed:17977944
    19. Moser M, Nieswandt B, Ussar S, Pozgajová M, Fassler R (2008) Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med 14:325-330 (A01) Pubmed:18278053
    20. Rauchfuss S, Geiger J, Walter U, Renné T, Gambaryan S (2008) Insulin inhibition of platelet-endothelial interaction is mediated by insulin effects on endothelial cells without direct effects on platelets. J Thromb Haemost 6:856-864 (A02;A03) Pubmed:18284601
    21. Rentsendorj O, Mirzapoiazova T, Adyshev D, Servinsky L, Renné T, Verin A, Pearse D (2008) Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function. Am J Physiol Lung Cell Mol Physiol 294:L686-L697 (A03) Pubmed:18281604
    22. Schlegel N, Burger S, Golenhofen N, Walter U, Drenckhahn D, Waschke J (2008) The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization. Am J Physiol Cell Physiol 294:C178-188 (A02;A04) Pubmed:17989211
    23. Schreier B, Börner S, Völker K, Gambayran S, Schäfer SC, Kuhlencordt P, Gassner B, Kuhn M (2008) The heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansion. Endocrinology 149:4193-4199 (A07; A02) Pubmed:18450968
    24. Templin C, Kotlarz D, Faulhaber J, Schnabel S, Grote K, Salguero G, Luchtefeld M, Hiller KH, Jakob P, Naim HY, Schieffer B, Hilfiker-Kleiner D, Landmesser U, Limbourg FP, Drexler H (2008) Ex vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: role of ß-catenin transduction and cell dose. J Mol Cell Cardiol 45:394-403 (B02, B03) Pubmed:18671980
    25. Varga-Szabo D, Braun A, Kleinschnitz C, Bender M, Pleines I, Pham M, Renné T, Stoll G, Nieswandt B (2008) The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction. J Exp Med 205:1583-1591 (A01;B01;A03) Pubmed:18559454
    26. Waller C, Hiller KH, Pfaff D, Gattenlohner S, Ertl G, Bauer WR (2008) Functional mechanisms of myocardial microcirculation in left ventricular hypertrophy: A hypothetical model of capillary remodeling post myocardial infarction. Microvasc Res 75:104-111 (B02, B10) Pubmed:17540413
    27. Zahedi RP, Lewandrowski U, Wiesner J, Wortelkamp S, Moebius J, Schutz C, Walter U, Gambaryan S, Sickmann A (2008) Phosphoproteome of resting human platelets. J Proteome Res 7:526-534 (A02) Pubmed:18088087


    1. Bauer WR, Nadler W (2008) Dynamics and efficiency of Brownian rotors. J Chem Phys 129:225103 (B05) Pubmed:19071949
    2. Bolender N, Sickmann A, Wagner R, Meisinger C, Pfanner N (2008) Multiple pathways for sorting mitochondrial precursor proteins. EMBO Rep 9:42-49 (A02) Pubmed:18174896
    3. Förster C (2008) Tight junctions and the modulation of barrier function in disease. Histochem Cell Biol 130:55-70 (A05) Pubmed:18415116
    4. Frantz S, Ertl G, Bauersachs, J (2008) Toll-like receptor signaling in the ischemic heart. Front Biosci 13:5772-5779 (A10) Pubmed:18508620
    5. Hiller KH, Waller C, Haase A, Jakob PM (2008) Magnetic Resonance of Cardiac Disease. Handbook of Experimental Pharmacology: Molecular Imaging II: Hrsg.: W. Semmler, M. Schwaiger, Springer Verlag Berlin Heidelberg Juli 2008, ISBN: 978-3-540-77449-5 (B02, B03)
    6. Klug G, Bauer L, Bauer WR (2008) Patterns of USPIO deposition in murine atherosclerosis. Arterioscler Thromb Vasc Biol 28:E157 (B04) Pubmed:18716317
    7. Rieckmann P (2008) Imatinib buys time for the brain after stroke. Nat Med 14:712-713 (A06) Pubmed:18607366
    8. Stoll G, Kleinschnitz C, Nieswandt B (2008) Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment. Blood 112:3555-3562 (B01;A01) Pubmed:18676880
    9. Varga-Szabo D, Pleines I, Nieswandt B (2008) Cell adhesion mechanisms in platelets. Arterioscler Thromb Vasc Biol 28:403-412 (A01) Pubmed:18174460
    10. Wiesner J, Premsler T, Sickmann A (2008) Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications. Proteomics 8:4466-4483 (A02) Pubmed:18972526
    11. Ziener CH, Kampf T, Herold V, Jakob PM, Bauer WR, Nadler W (2008) Frequency autocorrelation function of stochastically fluctuating fields caused by specific magnetic field inhomogeneities. J Chem Phys 129:014507 (B05, B03) Pubmed:18624483