Name: Marlene Strobel
PI: Prof. Dr. Dr. Andreas Beilhack
Institute: Department of Medicine II, University Hospital Würzburg
Funding: TRR124 FungiNet
Project: We investigate the benefit of an adoptive neutrophilic granulocyte transfer into neutropenic mice to combat invasive pulmonary infections caused by the saprophytic mold Aspergillus fumigatus. For this, we employ different neutrophil mobilization strategies to ensure high neutrophil numbers as well as neutrophils with boosted antifungal effector functions. The most important techniques for this project are multiparameter flow cytometry, non-invasive bioluminescence imaging, CLSM, and 3D light sheet fluorescence microscopy.