Name: Hannah Manz
PI: Prof. Dr. Dr. Andreas Beilhack, Dr. Andreas Brandl
Institute: Department of Medicine II, University Hospital Würzburg
Funding: µbone Consortium
Project: We aim to characterize the interaction of multiple myeloma cells with other cells from their local microenvironment in the bone marrow. Apart from classical 2D co‑cultures and flow cytometry, our major goal is to visualize these interactions using confocal and 3D light sheet fluorescence microscopy. Therefore, we want to establish a 3D model to mimic the physiological condition of the human bone marrow. Our overall goal use this model, to test specific treatment options in vitro.