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Rudolf-Virchow-Zentrum für Experimentelle Biomedizin

Stellenangebote

Folgende Stellen sind aktuell zu besetzen:

PhD student (f/m) in Nanophotonics & Biophysics
The research group Heinze at the Rudolf Virchow Center for Experimental Biomedicine of the University of Würzburg offers at the earliest possible date a position as

PhD student (f/m)
(Biophysics / Physics / Engineering)
In the field of Nanophotonics & Biophysics

In this cross-disciplinary approach we, the research group Heinze, combine high-resolution concepts of fluorescence microscopy with tricks from material sciences. Our approach involves designing and nanofabricating biocompatible nanostructured microscopy coverglasses for live cell applications that give rise to fundamentally new optical properties and the manipulation of light for superresolution imaging.

The project involves modelling, design and development of such metamaterial based substrates that serve as modified coverglasses for live-cell imaging. The overall goal is to detect conformational changes and cellular receptor interactions even for relatively large donor-acceptor-distances that are typically not accessible using classic (single molecule) imaging. The project particularly requires enthusiasm for biomolecular sciences, plasmonics and high-resolution microscopy.

We are interested in a PhD candidate with strong background in condensed matter physics holding a Master’s degree in Physics, Electrical Engineering or an equivalent level of professional qualification and experience. Ideally, the candidate has experience in thin film deposition and characterization. Advanced skills in experimental and numerical modeling of nanophotonic systems is mandatory. Experience in superresolution and single-molecule imaging is desired, however not a prerequisite.

The position is initially funded for a period of one year and will be extended in the case of a positive evaluation. The salary for this temporary position is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L. Female scientists are particularly encouraged to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.

Applications including cover letter, detailed CV, copies of certificates, and contact information of two referees, should be sent as a single pdf file (no more than 10 MB) via email to katrin.heinze@virchow.uni-wuerzburg.de  until 16th of Februrary 2019.

Lab page Heinze

What we offer

The successful candidate will work in the Rudolf Virchow Center using state-of-the-art technologies. We offer an international and multi-disciplinary environment with a strong expertise in the biophysics research field. Currently the research group consists of 10 members at different levels of seniority; post-doctoral scientists, PhD students, master students and research assistants. The successful applicant will have the opportunity to enroll in the ‘Graduate School of Life Sciences’ in Würzburg – an international graduate program. The University offers practical support and advice to the successful candidate concerning administrative and practical matters relating to the start of your employment and the process of moving to Würzburg (Welcome Center). The Research Academy of the University supports researchers in their individual science career. More information

Why do your PhD in Germany?

Latest publication and press release

Postdoc Positions in Platelet Research

The Department of Experimental Biomedicine at the
Rudolf Virchow Center/University Hospital Würzburg invites applications for

3 Postdoc Positions (f/m/d)

Platelet activation at sites of vascular injury is essential for hemostasis, but in diseased vessels it can also lead to ischemic events, such as heart attack and stroke. Moreover, the interaction of platelets with cells of the immune system (“thrombo-inflammation”) is critically involved in the pathogenesis of inflammatory disease states. The production of platelets by their bone marrow precursor cells, the megakaryocytes, is tightly controlled and disturbances in this process may result in hemorrhagic disorders and vascular defects.
We focus on transgenic mouse models to study the roles of regulatory proteins (receptors, signaling molecules, cytoskeletal components) for platelet production and function in vitro and in vivo. Our research will yield novel insights into the process of platelet biogenesis and the complex functions of platelets in cardiovascular disease. Our long-term goal is to identify novel targets for the development of improved therapies against vascular diseases.


We are seeking excellent Postdocs to work on the following research topics:
1) Mechanisms of megakaryocyte polarization and platelet biogenesis
2) Signal transduction in platelet adhesion
3) Protein-protein interactions in platelet receptor signaling

Activities and responsibilities
The projects 1) and 2) will include the use of cutting edge in vitro and in vivo imaging techniques, cell biology, molecular biology, biochemistry, disease models and mouse genetics, and will have a strong biomedical/translational context. Project 3) will focus on biochemical analyses of protein-protein interaction, characterization of receptor-ligand interaction and protein engineering for preclinical therapeutic approaches. As a postdoctoral fellow in our group you will drive your own research project and collaborate closely with other group members, as well as local and international collaboration partners. You will furthermore engage in (co-)supervising PhD students and teaching activities.


You have / Qualification profile
Suitable candidates should hold a doctoral degree in biomedicine, pharmacy, biochemistry, biology or a related field and have a strong interest in molecular and (vascular) cell biology/immunology, mouse models, different imaging techniques, as well as translational disease-oriented research. Excellent knowledge of the English language is a prerequisite. For positions 1) and 2) previous experience with genetic mouse models, preferably in the field of vascular biology, is highly advantageous. For position 3) we seek an applicant with previous experience with (preferably mammalian) expression systems, protein purification and structural biology. As a postdoc in our group you should be able to drive and contribute to research projects and independently develop new research ideas.


Why join us / Benefits
All projects are embedded in the collaborative research center/transregio CRC/TR 240 – “Platelets – Molecular, cellular and systemic functions in health and disease” funded by the German research foundation (DFG) which provides a research environment and infrastructure that is unique in the platelet field. The projects furthermore involve the close interaction with long-standing international collaboration partners.
Our department is situated within the Rudolf Virchow Center, an international research center of the University of Würzburg which is part of the Medical Campus of University Hospital Würzburg. The Center provides an inter-disciplinary working environment using state-of-the-art infrastructure. The university offers also a comprehensive services concerning administrative and practical matters, e.g. the Welcome Centre (moving to Würzburg), the International Office, the Family Services as well as the JMU Research Academy (professional support and development) - see www.platelets.eu/career/.
The salary for these positions is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L. The positions are initially limited for two years with the possibility of extension. We particularly encourage female scientists to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.


Send applications to
The positions will start on March 1st, 2019 or later. Applications should be sent as one single pdf-document including application letter, curriculum vitae, certificates and 3 references by e-mail until February 15th, 2019 to The Würzburg Platelet Group / Prof. Bernhard Nieswandt (career@platelets.eu)
Please see our homepage (www.platelets.eu/career/) for further details on the positions.

PhD Student Positions in Platelet Research

The Department of Experimental Biomedicine at the
Rudolf Virchow Center/University Hospital Würzburg invites applications for

6 PhD student positions (f/m/d)

Platelet activation at sites of vascular injury is essential for hemostasis, but in diseased vessels it can also lead to ischemic events, such as heart attack and stroke. Moreover, the interaction of platelets with cells of the immune system (“thrombo-inflammation”) is critically involved in the pathogenesis of inflammatory disease states.
The production of platelets by their bone marrow precursor cells, the megakaryocytes, is tightly controlled and disturbances in this process may result in hemorrhagic disorders and vascular defects.
We focus on transgenic mouse models to study the roles of regulatory proteins (receptors, signaling molecules, cytoskeletal components) for platelet production and function in vitro and in vivo. Our research will yield novel insights into the process of platelet biogenesis and the complex functions of platelets in cardiovascular disease. Our long-term goal is to identify novel targets for the development of improved therapies against vascular diseases.

Activities and responsibilities
We are seeking highly motivated PhD students to work on the following research projects:
1) Studying platelet receptor signaling and regulation by superresolution and expansion microscopy
2) Platelet glycoprotein ectodomains: biochemical basis of systemic action
3) Advanced in vivo microscopy of platelet-vessel wall interaction in inflammation and cancer
4) Mechanisms of divalent cation signaling in platelets and megakaryocytes
5) Crosstalk of chronic inflammation and megakaryopoiesis
6) Platelets in resolution of liver inflammation and tissue regeneration

The projects will include the use of cutting edge in vitro and in vivo imaging techniques, cell biology, molecular biology, biochemistry, disease models and mouse genetics, and will have a strong biomedical/translational context.
Please see https://www.platelets.eu/career/phd-positions/ for further details.

Qualification profile
Suitable candidates should hold a Master’s degree or equivalent in a life sciences subject with a strong interest in molecular and (vascular) cell biology/immunology, mouse models and different imaging techniques. Excellent lab skills and good knowledge of the English language are a prerequisite. Previous experience with genetic mouse models and/or in vivo work is highly advantageous.

Benefits
We offer an international and excellent scientific environment that is embedded in the framework of a new German wide research consortium on platelets (www.tr240.de). Its infrastructure is unique in the platelet research field and offers the opportunity to collaborate with national and international basic and translational research groups. The research lab consists of several post-doctoral scientists, PhD students, master students and research assistants.
As a PhD student you will have the opportunity to become part of the international ‘Graduate School of Life Sciences’ (GSLS). The university furthermore offers a comprehensive services concerning administrative and practical matters, e.g. the Welcome Centre (moving to Würzburg) and the International Office.
The salary for this temporary position is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L). We particularly encourage female scientists to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.

Send applications to
The position will start on February 1st, 2019 or later. Applications should be sent as one single pdf-document including application letter, curriculum vitae, certificates and 2 references by e-mail until January 31, 2019 to
Prof. Bernhard Nieswandt / Dr. David Stegner (career@platelets.eu)
For further questions please do not hesitate to contact Dr. David Stegner: career@platelets.eu.

Platelet Research in Würzburg

Why do your PhD in Germany?

Studentische Hilfskräfte (m/w) im Schülerlabor "Virchowlab"

Wissenschaftliche Mitarbeiter: Studentische Hilfskräfte (m/w) im Schülerlabor "Virchowlab"

Wir suchen ab sofort Studenten (m/w) der Biologie, Biomedizin, Biochemie, Lehramt Biologie o.ä. mit Laborerfahrung, die mittwochs und/oder donnerstags von 9:00-15:30 Uhr Schüler im Schülerlabor bei naturwissenschaftlichen Experimenten anleiten

Das "Virchowlab" will Schulen in der naturwissenschaftlichen Ausbildung unterstützen und durch lehrplanvertiefendes Experimentieren das Interesse an Naturwissenschaften fördern. Dazu können sie in CSI Würzburg dem „Labor-Mörder“ auf die Fährte kommen, grüne Proteine isolieren, lernen, wie schnell sich Infektionen verbreiten.

Als Betreuer/in unterstützen Sie die Kinder bzw. Schüler beim Experimentieren, erarbeiten mit ihnen zusammen die Hintergründe der Versuche und erzählen ihnen, wie das Forscherleben aussieht. Sie bereiten die Versuche vor und nach.
Die Stellen können für ein oder zwei Semester angenommen werden, Verlängerungen sind möglich. Insgesamt sind es mehrere Betreuer, so dass die Betreuungszeiten mit dem Studium abgestimmt werden können. Es besteht auch die Möglichkeit bei längerer Betreuerzeit eventuell ECTS-Punkte für die Schlüsselqualifikation zu bekommen.

Das Schülerlabor bietet Ihnen eine hervorragende Möglichkeit praktische Laborerfahrungen zu sammeln. Ein nicht zu unterschätzendes Plus bei späteren Bewerbungen.

Sie trauen sich zu, mit Schülern umzugehen und haben Lust, ihnen zu zeigen, dass Forschung Spaß macht? Ihr Semesterplan hat ab Februar 2019 am Donnerstag (eventuell Mittwoch) eine Lücke und Sie möchten sich etwas dazuverdienen? Dann stellen Sie sich per eMail kurz bei uns vor und schreiben Sie uns, warum Sie das Virchowlab oder Rudis Forschercamp betreuen möchten. Diese formlose Kurzbewerbung schicken Sie bitte an: katja.weichbrodt@virchow.uni-wuerzburg.de

Bewerbungen von Frauen sind besonders erwünscht. Schwerbehinderte Bewerber/innen werden bei im Wesentlich gleicher Eignung bevorzugt eingestellt.

Kontakt

Frau Katja Weichbrodt
Public Science Center
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-Straße 2, Haus D15
D - 97080 Würzburg

Tel.:     +49 931 31-80377
E-Mail: katja.weichbrodt@virchow.uni-wuerzburg.de

Studentische Hilfskräfte (m/w) für "Rudis Forschercamp"

Wissenschaftliche Mitarbeiter: Studentische Hilfskräfte (m/w) für "Rudis Forschercamp"

Wir suchen ab sofort Studenten (m/w) der Biologie, Biomedizin, Biochemie, Lehramt Biologie o.ä. mit Laborerfahrung, die donnerstags von 15:30 - 18:00 Uhr Schüler im Schülerlabor bei naturwissenschaftlichen Experimenten anleiten

In "Rudis Forschercamp" können Kinder (von 8-12 Jahren) in Kleingruppen unter Anleitung in den Bereichen Physik, Chemie, Medizin und Biologie selbstständig experimentieren. Das Schülerlabor bietet den Studenten (m/w) eine hervorragende Möglichkeit, sich Lehrerfahrung anzueignen. Ein nicht zu unterschätzendes Plus bei späteren Bewerbungen.

Bewerbungen von Frauen sind besonders erwünscht. Schwerbehinderte Bewerber/innen werden bei im Wesentlich gleicher Eignung bevorzugt eingestellt.

Bitte richten Sie Ihre Bewerbung per Email an:

Katja Weichbrodt

Public Science Center
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-Straße 2, Haus D15
D - 97080 Würzburg

Tel.:     +49 931 31-80377
E-Mail: katja.weichbrodt@virchow.uni-wuerzburg.de

Hinweis zum Datenschutz

Mit 'OK' verlassen Sie die Seiten der Universität Würzburg und werden zu Facebook weitergeleitet. Informationen zu den dort erfassten Daten und deren Verarbeitung finden Sie in deren Datenschutzerklärung.

Hinweis zum Datenschutz

Mit 'OK' verlassen Sie die Seiten der Universität Würzburg und werden zu Twitter weitergeleitet. Informationen zu den dort erfassten Daten und deren Verarbeitung finden Sie in deren Datenschutzerklärung.

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Kontakt

Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Josef-Schneider-Straße 2
Haus D15
97080 Würzburg

E-Mail

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