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Rudolf-Virchow-Zentrum für Experimentelle Biomedizin

Stellenangebote

Folgende Stellen sind aktuell zu besetzen:

PhD student (Physics / Engineering) in Nanophotonics & Biophysics

A PhD student position is available in the lab of Prof. Katrin Heinze at the Rudolf Virchow Center for Experimental Biomedicine

The Rudolf Virchow Center of the University of Würzburg offers at the earliest possible date a position as

PhD student (f/m)
(Physics / Engineering)
in the field of Nanophotonics & Biophysics.

In this cross-disciplinary approach we combine high-resolution concepts of fluorescence microscopy with tricks from material sciences. Our approach involves designing and nanofabricating biocompatible nanostructured microscopy slides and coverglasses for live cell applications that give rise to fundamentally new optical properties and the manipulation of light for superresolution imaging.

The project involves modelling, design and development of such metamaterial based substrates that serve as modified coverglasses for live-cell imaging. The overall goal is to detect conformational changes and cellular receptor interactions even for relatively large donor-acceptor-distances that are typically not accessible using classic (single molecule) imaging. The project particularly requires enthusiasm for biomolecular sciences, plasmonics and high-resolution microscopy.

We are interested in a PhD candidate with strong background in condensed matter physics holding a Master’s degree in Physics, Electrical Engineering or an equivalent level of professional qualification and experience. Ideally, the candidate has experience in thin film deposition and characterization. Advanced skills in experimental and numerical modeling of nanophotonic systems is mandatory. Experience in superresolution and single-molecule imaging is desired, however not a prerequisite.

The position is initially funded for a period of one year and will be extended in the case of a positive evaluation. The salary for this temporary position is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L (E13 (65%) for a three-year dissertation).Female scientists are particularly encouraged to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.

Applications including cover letter, detailed CV, copies of certificates, and contact information of two referees, should be sent as a single pdf file (no more than 10 MB) via email to katrin.heinze@virchow.uni-wuerzburg.deuntil 15th December 2018.

Research Group Heinze (lab page)

What we offer at the University and in Würzburg

Research Assistant/Postdoc Position - Bio-Imaging Center

A Research Assistant / Postdoc position is available in the lab of Prof. Katrin Heinze at the Rudolf Virchow Center for Experimental Biomedicine

The Rudolf Virchow Center of the University of Würzburg offers at the earliest possible date a position as

Research Assistant / Postdoc
TV-L/E13 (50%)
at the Bio-Imaging Center
in "Integrated data management“

The position will support the Infrastructure (INF) project of the Transregional Collaborative Research Center SFB-TR240. This INF project consists of The Virtual Platelet Platform ViPP and its teaching modules ViPP-Class.

The position includes data management, particularly the integration and navigation of didactic elements and teaching tools on our website and related platforms such as Moodle. Support in recording and streaming of lectures as well as maintenance and data storage of large imaging data sets will also play a role. Ideally, the candidate has experience in informatics or/and data management, and good computer skills. Fluent English as well as the willingness to deal with complex data sets are essential. A suitable candidate enjoys working with an interdisciplinary team of scientists and engineers. Work experience in life sciences and imaging is desirable, but not mandatory.

The salary is based on TV-L (E13). The position is part-time (50%), and initially fixed-term. Female candidates are particularly encouraged to apply. Disabled applicants will be preferentially considered in case of equivalent qualification.

Applications including cover letter, detailed CV, copies of certificates, and contact information of two referees, should be sent before 22th November 2018 to katrin.heinze@virchow.uni-wuerzburg.de

Website Heinze

What we offer

What Würzburg offers

PhD Position - From Molecular Mechanisms to Disease

PhD position: From Molecular Mechanisms to Disease

At the Rudolf-Virchow-Center for Experimental Biomedicine at the University of Würzburg within the group of Prof. Dr. Caroline Kisker we are looking for a highly motivated PhD student.

The posttranslational modification of proteins by ubiquitin has taken center stage in eukaryotic cell biology. Abnormalities of the ubiquitin system causally contribute to the pathogenesis of multiple human diseases including cancer, neurodegenerative disorders and infectious diseases. However, limited mechanistic insights into the affected components of the ubiquitin system still present an obstacle to the design of efficient therapeutic strategies.

In this call we seek for a PhD student who will focus on the deubiquitinases Cdu1 and Cdu2 from Chlamydia trachomatis and their interaction partners. We aim to obtain a detailed understanding of how these DUBs are employed by the pathogen to invade its host thereby generating a protected niche for proliferation, survival or persistence. The work will include the identification of novel host interaction partners and the analysis of structural and functional aspects of their interactions.

The successful applicant will work within the GRK2243, a DFG-funded doctoral program which integrates internationally recognized research groups in a unique collaborative framework to study key mechanisms of the ubiquitin system underlying human diseases. It provides an excellent platform for research and training using state-of-the-art technologies in structural biology, biochemistry, molecular cell biology, tumor biology, microbiology, functional genomics, in silico drug design and proteomics. The research program is complemented by scientific seminars and workshops, as well as career de-velopment opportunities offered jointly with the Graduate School of Life Sciences at the University of Würzburg.

The position is fully funded and available immediately. The salary will be according to the German TV-L scale (65%). Disabled applicants will be preferentially considered in case of equivalent qualifications.

Interested applicants should contact Teresa Frank (Teresa.Frank@virchow.uni-wuerzburg.de), providing a letter of motivation outlining scientific interests and previous research experiences (max 2 pages), a CV (max. 1 page), transcripts of the Master degree certificate and the contact information for at least two references.

Prof. Dr. Caroline Kisker
Chair of the Rudolf Virchow Center
University of Würzburg
Josef-Schneider-Straße 2, Haus D15
97080 Würzburg
Germany

Lab Page

PhD Position - Structural Biology / DNA repair

A PhD position is available in the lab of Prof. Caroline Kisker at the Rudolf Virchow Center for Experimental Biomedicine

The Kisker Lab investigates the structural and functional organization of eukaryotic DNA repair processes and genomic integrity, utilizing protein-crystallographic, cryo-EM, biophysical as well as biochemical approaches. The successful candidate will join a well-established research group with experienced colleagues and state-of-the art equipment. The project aims to decipher the role of different essential proteins in genome integrity by the above described methods. The successful applicant will further be enrolled into the Graduate School of Life Sciences, an international PhD program of the University of Wuerzburg, which offers a structured doctoral research training and a wide range of interdisciplinary courses and activities.

We are looking for highly motivated candidates with a strong interest in protein structure-function analysis, who should hold an M.Sc. or comparable degree in biochemistry, molecular biology, chemistry or a related discipline. Experience in protein purification, protein biochemistry, biophysical or structural techniques is beneficial. Fluency in English is essential. German language skills are optional.

The position is fully funded and available immediately. The salary will be according to the German TV-L scale (65%). Disabled applicants will be preferentially considered in case of equivalent qualifications.

Interested applicants should contact Teresa Frank (Teresa.Frank@virchow.uni-wuerzburg.de), providing a letter of motivation outlining scientific interests and previous research experiences (max 2 Pages), a CV (max. 1 Page), transcripts of the Master degree certificate and the contact information for at least two references. 

Starting date: As soon as possible

Prof. Dr. Caroline Kisker
Rudolf Virchow Center for Experimental Biomedicine
University of Wuerzburg
Josef-Schneider-Straße 2, Haus D15
97080 Würzburg
Germany

Lab Page

PhD positions - Molecular, cellular and systemic functions of platelets in health and disease

The Institute of Experimental Biomedicine I, Rudolf Virchow Center & University Hospital Würzburg, Germany offer six PhD positions, embedded in the newly DFG-funded Collaborative Research Center CRC/TR 240 “Platelets – Molecular, cellular and systemic functions in health and disease”.

PhD positions will be connected to the following major research topics:

a.    Impact of irradiation on the bone marrow niche and platelet biogenesis

b.    Optogenetic approaches in platelet production

c.     Role of the platelet cytoskeleton in platelet mechanics

d.    Ion homeostasis in megakaryopoiesis and platelet function

e.    Platelets as modulators of neuro-inflammation

f.      Platelets in resolution of liver inflammation

Candidates with a Master degree in life sciences and interests in cell biology, molecular biology, biophysics, time-lapse imaging, mouse in vivo models, and advanced microscopic techniques are encouraged to apply. Successful candidates are expected to prove excellent lab skills. Good English skills are essential.

We offer the possibility to work on highly innovative projects in an excellent scientific environment and to collaborate with national and international research groups. The successful applicants will have the opportunity to enroll in the ‘Graduate School of Life Sciences’ in Würzburg – an international graduate program.

All positions open on July 1st, 2018 or later. Salary is based on TV-L (E-13, 65%). Disabled applicants will be preferentially considered in case of equivalent qualification. The University Hospital of Würzburg seeks to increase the number of women and therefore explicitly encourages them to apply.

Interested candidates should send their application by Email, specifying their topic of interest, until July 13th, 2018 including curriculum vitae, a brief description of past research experience and references to Bender_M1@ukw.de(preferably as one PDF file in an email attachment).

Chair:Prof. Dr. Bernhard Nieswandt
Lehrstuhl für Experimentelle Biomedizin
Josef-Schneider-Str. 2, Haus D15
97080 Würzburg

 

Related News

Targeting platelets
A new Collaborative Research Center will start in July with a total funding of nearly 14 million euros, headed by the German Institute for Experimental Biomedicine in Würzburg. The aim is to decode the complex and insufficiently understood functions of platelets, the so-called thrombocytes. The scientists hope to use these findings to gain new insights into platelet research which allow better treatment of conditions such as heart attack, stroke, acute lung failure and cancer.

 

Latest Publication

Studentische Hilfskräfte (m/w) im Schülerlabor "Virchowlab"

Wissenschaftliche Mitarbeiter: Studentische Hilfskräfte (m/w) im Schülerlabor "Virchowlab"

Wir suchen ab sofort Studenten (m/w) der Biologie, Biomedizin, Biochemie, Lehramt Biologie o.ä. mit Laborerfahrung, die dienstags und/oder donnerstags von 9:00-15:30 Uhr Schüler im Schülerlabor bei naturwissenschaftlichen Experimenten anleiten

Das "Virchowlab" will Schulen in der naturwissenschaftlichen Ausbildung unterstützen und durch lehrplanvertiefendes Experimentieren das Interesse an Naturwissenschaften fördern. Dazu können sie in CSI Würzburg dem „Labor-Mörder“ auf die Fährte kommen, grüne Proteine isolieren, lernen, wie schnell sich Infektionen verbreiten.

Das Schülerlabor bietet den Studenten (m/w) eine hervorragende Möglichkeit sich Lehrerfahrung anzueignen. Ein nicht zu unterschätzendes Plus bei späteren Bewerbungen.

Bewerbungen von Frauen sind besonders erwünscht. Schwerbehinderte Bewerber/innen werden bei im Wesentlich gleicher Eignung bevorzugt eingestellt.

Bitte richten Sie Ihre Bewerbung per Email an:

Katja Weichbrodt

Public Science Center
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-Straße 2, Haus D15
D - 97080 Würzburg

Tel.:     +49 931 31-80377
E-Mail: katja.weichbrodt@virchow.uni-wuerzburg.de

Studentische Hilfskräfte (m/w) für "Rudis Forschercamp"

Wissenschaftliche Mitarbeiter: Studentische Hilfskräfte (m/w) für "Rudis Forschercamp"

Wir suchen ab sofort Studenten (m/w) der Biologie, Biomedizin, Biochemie, Lehramt Biologie o.ä. mit Laborerfahrung, die donnerstags von 15:30 - 18:00 Uhr Schüler im Schülerlabor bei naturwissenschaftlichen Experimenten anleiten

In "Rudis Forschercamp" können Kinder (von 8-12 Jahren) in Kleingruppen unter Anleitung in den Bereichen Physik, Chemie, Medizin und Biologie selbstständig experimentieren. Das Schülerlabor bietet den Studenten (m/w) eine hervorragende Möglichkeit, sich Lehrerfahrung anzueignen. Ein nicht zu unterschätzendes Plus bei späteren Bewerbungen.

Bewerbungen von Frauen sind besonders erwünscht. Schwerbehinderte Bewerber/innen werden bei im Wesentlich gleicher Eignung bevorzugt eingestellt.

Bitte richten Sie Ihre Bewerbung per Email an:

Katja Weichbrodt

Public Science Center
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Universität Würzburg
Josef-Schneider-Straße 2, Haus D15
D - 97080 Würzburg

Tel.:     +49 931 31-80377
E-Mail: katja.weichbrodt@virchow.uni-wuerzburg.de

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Rudolf-Virchow-Zentrum für Experimentelle Biomedizin
Josef-Schneider-Straße 2
Haus D15
97080 Würzburg

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