Deutsch Intern
    Rudolf Virchow Center for Integrative and Translational Bioimaging

    GRK Guest Speaker: Prof. Katrin Rittinger

    "Structural and mechanistic characterisation of multi-domain E3 ligases that regulate immune signalling"
    Date: 07/08/2019, 5:00 PM - 6:00 PM
    Category: englisch
    Location: Medizin, Geb. D15, 01.002-004
    Organizer: Research Training Group 2243
    Speaker: Prof. Katrin Rittinger

    Prof. Katrin Rittinger from The Francis Crick Institute London (UK) will be our guest at the RVZ, in collabortion with the DFG Research Training Group 2243.

    "Our research is focused on the characterisation of the mechanism of two different families of E3 ubiquitin ligases, the RBR (RING-Between-RING) family and the TRIM (tripartite motif) family using a combination of structural, biochemical and biophysical approaches. Members of both of these E3 families have been shown to play important regulatory roles in immune and inflammatory signalling and defects in their activity have been linked to a number of diseases. In this talk I will present recent work aimed at developing tools that help study E3 ligase function in a physiological context and describe the interplay between protein ubiquitination and host defence."

    More details about her research: Website.

    Everybody is welcome to attend.


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