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Deutsch Intern
Rudolf Virchow Center for Experimental Biomedicine

Microarrays and Peptide Synthesis

The following techniques are available to all research groups:

Peptide Synthesis and Purification

Contact: Group Maric

Parallel synthesis and purification of up to 1536 small proteins (routinely up to 40 residues), peptides and peptidic compounds, in nano gram to gram scale. Chemical modification of resulting molecules with functional groups for numerous applications including imaging and immobilisation.

 

Peptide and Protein Microarray applications

Contact: Group Maric

Peptides and expressed proteins are immobilized in femto molar scale on solid surfaces using automated printers. Resulting libraries are used to screen, identify or quantify protein-protein interactions in high-throughput with low sample consumption. Applications include epitope mapping, fine mapping of protein interaction sites, affinity maturation and definition of consensus sequences.