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Rudolf Virchow Center for Integrative and Translational Bioimaging

Press Archive

Press Archiv

Attack via byways

11/14/2022
Dimeric structure of phosphoglycolate phosphatase. The enlarged section on the right shows the ligand-binding pocket in complex with the small molecule inhibitor CP1.

Increased cell proliferation is a key feature of diseases such as cancer. A research team from the University of Würzburg and two Leibniz Institutes has now succeeded in indirectly influencing this process.

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The photoswitching rates of fluorescent dyes are as unique as a fingerprint and as readable as a barcode.

Researchers at the University of Würzburg develop the "photoswitching fingerprint analysis". A unique technology that for the first time allows the analysis of molecular processes and the regulation of individual proteins in living cells with sub-10 nm spatial resolution. The application ranges from biological to medical research and has been published in the renowned journal Nature Methods.

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Microscopy showing the fragmentation of mitochondria

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

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Cerebral venous thrombosis is a rare, often severe disease that has been brought to public attention by the Covid 19 pandemic. A research group from Würzburg has now succeeded for the first time in deciphering a molecular cause of this disease. This opens the way to new therapeutic approaches. Published in Nature Cardiovascular Research.

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Their work is most frequently cited in publications of other scientists. Four researchers from the University are therefore included in the Highly Cited Researchers 2021 List.

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The RVZ, like Rudolf Virchow, is celebrating an anniversary this year - it has been there for 20 years! From the very beginning, we have been engaged in thematically broad cutting-edge research.

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Dr. Gerti Beliu has started a new research group at the Rudolf Virchow Center of the University of Würzburg in September. He uses novel techniques to exploit the resolution of microscopy more effectively and to develop new applications for biomedicine.

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Professor David Stegner recently accepted the professorship of Vascular Imaging at the Rudolf Virchow Center. With his group, he studies the interactions of blood platelets with immune cells and how these affect inflammatory processes such as stroke.

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