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    Rudolf Virchow Center for Integrative and Translational Bioimaging

    RVZ News

    News

    Their work is most frequently cited in publications of other scientists. Four researchers from the University are therefore included in the Highly Cited Researchers 2021 List.

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    The RVZ, like Rudolf Virchow, is celebrating an anniversary this year - it has been there for 20 years! From the very beginning, we have been engaged in thematically broad cutting-edge research.

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    Dr. Gerti Beliu has started a new research group at the Rudolf Virchow Center of the University of Würzburg in September. He uses novel techniques to exploit the resolution of microscopy more effectively and to develop new applications for biomedicine.

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    Professor David Stegner recently accepted the professorship of Vascular Imaging at the Rudolf Virchow Center. With his group, he studies the interactions of blood platelets with immune cells and how these affect inflammatory processes such as stroke.

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    Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

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    We are inviting applications for a Group Leader (f/m/d) in Chemical Biology. The RVZ appoints group leaders early in their career and provides them with a supportive, collaborative environment and generous work package for their independent position. Significant core funding and limited teaching responsibilities will allow you to embark on a visionary research program.

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    Scientists from the University of Würzburg and the University of Strasbourg identified a new important molecular region in an essential human DNA repair complex, consisting of the proteins XPD and MAT1. This complex forms a central unit in the nucleotide excision DNA repair mechanism (NER) and thus protects our genetic information. The findings were published in the journal Nature Communications and could provide new starting points for cancer therapy.

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    On 23th March 2020, Professor Katrin Heinze officially started her new “Chair of Molecular Microscopy" at the Medical Faculty of the Julius Maximilians University (JMU) Würzburg, Germany. The physicist will boost the development of precise microscopy methods for biomedical imaging and spectroscopy.

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    Picture of the structure of the cytochrome bd oxidase.

    Scientists from the University of Würzburg and the University of Freiburg succeeded in determining the complex molecular structure of the bacterial enzyme cytochrome bd oxidase. Since humans do not have this type of oxidase, this enzyme could be an interesting target for novel antibiotics.

     

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    A team of researchers lead by Helmholtz Zentrum München and the University of Würzburg identified an enzyme as a novel and strong inhibitor of ferroptosis, the iron dependent form of cell death: ferroptosis suppressor protein-1, short FSP1. This protein is expressed in a variety of cancer cell lines and therefore represents an attractive drug target for cancer treatment. The results were published in the journal Nature.

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    [Translate to Englisch:] Bild von Dr. Grzegorz Sumara

    For the foundation of the first two Dioscuri centers our RVZ group leader Dr. Grzegorz Sumara will return to Poland. The Grzegorz Sumara centre will focus on elucidating signalling pathways involved in metabolic diseases.

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