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IMIB - INSTITUTE OF MOLECULAR INFECTION BIOLOGY

Prof. Dr. Jörg Vogel - RNA Biology

 

 

     RESEARCH TOPIC

Model Organisms

Research

Non-coding RNAs play important regulatory roles in all domains of life. The group aims to understand the role of ncRNAs and RNA binding proteins (RBPs) in the context of bacterial infections, with the goal to use this knowledge for targeted manipulation of the human microbiota. The current four main areas of research in the Vogel lab are: i) discovery of novel functional RNAs in microbes, which includes work on the cancer-associated bug Fusobacterium nucleatum; ii) characterization of and screens for bacterial RNA-binding proteins; iii) new RNA-seq methods for infection biology, including single-cell RNA-seq of eukaryotic and bacterial cells; iv) antisense oligonucleotide (ASO)-based antibiotics for precision editing of the human microbiome and complex microbial communities.

Ponath F, Tawk C, Zhu Y, Barquist L, Faber F, Vogel J (2021)
RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum
Nature Microbiology 6(8):1007-1020

Westermann AJ, Förstner KU, Amman F, Barquist L, Chao Y, Schulte LN, Müller L, Reinhardt R, Stadler PF, Vogel J (2016)
Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions
Nature 529:496-501

Papenfort K, Sun Y, Miyakoshi M, Vanderpool CK, Vogel J (2013)
Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis
Cell 153:426–437

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E (2011)
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Nature 471(7340):602-7

Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiß S, Sittka A, Chabas S, Reiche K, Hackermüller J,
Reinhardt R, Stadler PF, Vogel J (2010)
The primary transcriptome of the major human pathogen Helicobacter pylori
Nature 464(7285)250-255

Publications chronological (pdf)

Publications sorted (pdf)

Prof. Dr. Jörg Vogel

Director
Chair Molecular Infection Biology I
Vogel Group
Building: D15
Room: 01.022
Phone: +49 931 31-82576
[Translate to Englisch:]

Leandro Buhlmann

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.025
Phone: +49 931 31-84789
[Translate to Englisch:]

Valentina Cosi

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.026
Phone: +49 931 31-83301
[Translate to Englisch:]

Victoria Gebler

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.020
Phone: +49 931 31-82337

Dr. Chandradhish Ghosh

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.020
Phone: +49 931 31-83762
[Translate to Englisch:]

Dr. Esther Hauschild

Technician
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.203
Phone: +49-931-31-87292
[Translate to Englisch:]

Dr. Fabian Imdahl

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 02.047
Phone: +49 931 31-88471

Jakob Jung

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.051
Phone: +49 931 31-87151
Link: PhD Project
[Translate to Englisch:]

Zumra Khan-Saif

Technician
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.203
Phone: +49 931 31-85730

Dr. Willow Kion-Crosby

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.029
Phone: +49 931 31-87721

Luise Klos

Technician
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.203
Phone: +49 931 31-83044

Vincent Lau

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.020
Phone: +49 931 31-86823

Sarah Nentwich

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.025
Phone: +49 931 31-86287
[Translate to Englisch:]

Barbara Plaschke

Technician
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.203
Phone: +49-931-31-80431
[Translate to Englisch:]

Dr. Linda Popella

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.020
Phone: +49 931 31-87481
[Translate to Englisch:]

Dr. Gauthier Roy

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.026
Phone: +49 931 31-85117

Dr. Paramita Sarkar

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Phone: +49 931 31-84992
[Translate to Englisch:]

Julia Seidel

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.025
Phone: +49 931 31-85709

Hanna Weidt

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.026
Phone: +49 931 31-83543

Dr. Toby Wilkinson

Postdoc
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.020
Phone: +49 931 31-81869
[Translate to Englisch:]

Yan Zhu

PhD Student
Institute of Molecular Infection Biology
Vogel Group
Building: D15
Room: 01.026
Phone: +49-931-31-99914
[Translate to Englisch:]