Job Offers
The Nanoscale Bacteriology Lab in the Rudolf Virchow Center for Center for Integrative and Translational Bioimaging at the University of Würzburg, Germany, invites applications for
PostDoc position in infection biology and advanced imaging (f/m/d)
The Nanoscale Bacteriology Lab, led by Dr. Christoph Spahn, is looking for a PostDoc to study the intracellular organization of intracellular pathogens during infection.
Our research focusses on understanding the subcellular organization of bacteria and their response to antimicrobial compounds. We combine super-resolution microscopy (Spahn et al., 2018), drug treatments (Spahn et al., 2025) artificial intelligence (Spahn et al., 2022) and biochemical approaches to understand both fundamental concepts of bacterial cell biology and antibiotic action. Recently, we started to investigate how secretion alters the intracellular organization of pathogens (Ermoli et al., 2025).
In the advertised position, the successful candidate will investigate bacterial secretion during host-pathogen interaction. We will employ a combinatorial approach using live-cell imaging, multicolor super-resolution microscopy and genetics to gain fundamental knowledge about the dynamics of effector protein secretion and the effect on both host cells and pathogens.
Qualification profile:
As a PostDoc applicant, you have completed a PhD in life sciences or related fields.
Essential qualifications
- Enthusiasm for science/basic research
- A strong background in the field of life sciences
- Experience in infection biology and/or molecular biology of bacterial pathogens
- Experience in bacterial and mammalian cell culture
- Experience in advanced microscopy and image analysis
- Curiosity to learn new techniques and explore novel ground
- Excellent team spirit and willingness to teach students
- Fluent English
Optional qualifications
- Experience in programming or with AI
- Experience in biochemistry
What we offer:
At Julius-Maximilians-Universität Würzburg, more than 30,000 people from over 100 countries come together to study, research, teach and work. As a central institution of the University, the Rudolf Virchow Center is a modern research center with more than 100 international scientists investigating the molecular causes of health and disease. It has been established as a unique institution for translational bioimaging combining all existing imaging core structures and microscopy facilities.
The Rudolf Virchow Center is a highly competitive international research institute with an outstanding infrastructure. We have in-house access to state-of-the-art instrumentation and to an extensive range of modern biophysical and cell biological equipment. We are integrated into a stimulating cross-disciplinary environment that includes our partners at the Biocenter, the physics department, the Max Planck Research Group in Systems Immunology, the Institute for Molecular Infection Biology (IMIB), Helmholtz Institute for RNA-based Infection Research (HIRI) and the University Hospital in Würzburg.
Würzburg is located in the beautiful, wine-growing area of Franconia, in proximity of Frankfurt (1 hour by train) and Munich (2 hours). We have a lot of sun and many festivals in the summer, as well as impressive historical buildings and recreative nature.
The salary is commensurate with training and experience according to Collective Agreement for the Public Service of German Federal States TV-L (100%).
You will have access to both national and public-service pension schemes (VBL), health care, and are entitled to 30 days of holiday in addition to 13 annual public holidays in Bavaria. Our Welcome Center supports international candidates in finding accommodation as well as in administrative matters - and the University of Würzburg offers support for researchers with children, including flexible working hours and childcare.
The position is secured until end of 2028.
Interested?
Applications including a cover letter, a detailed CV (2 pages max), a short summary of past research projects with publications (3 pages max), copies of certificates, and the contact information of two referees, should be sent via email as a single pdf file (not exceeding 10 MB). Applications will be screened continuously until the position is filled.
The University of Würzburg is an equal opportunity employer. As such, we explicitly encourage applications from qualified women.
Please send your application to:
Christoph.spahn@uni-wuerzburg.de with Cc to Inka.robinson@uni-wuerzburg.de
If you want to know more about the individual project and/or have further questions about the position, please contact me via the mail above.
At the Rudolf Virchow Center (RVZ) of the Julius Maximilian University of Würzburg,
A position as
Student Research Assistant (HiWi)
(w, m, d; Bachelor’s degree)
is available with immediate effect
(approx. 37 hours/month, 12-month contract).
To provide technical assistance on the project
Mechanisms of glycoprotein (GP)VI-driven emergency platelet production
In a cross-disciplinary and highly translational approach, we combine in vivo, ex vivo, and in vitro experimental strategies to investigate platelet biogenesis under stress conditions.
The position is aimed at providing technical and experimental support for a research project investigating the function of glycoprotein VI (GPVI) in bone marrow–resident megakaryocytes (MKs) and its contribution to platelet production, with a specific focus on emergency thrombopoiesis. Despite the central role of GPVI in platelet activation, its function in MK biology remains largely unexplored. Under supervision, you will support experiments involving primary cells, mouse models, and molecular and cellular biology techniques, assist with sample preparation, data acquisition, and documentation, and contribute to the characterization of mechanisms underlying stress-induced platelet production.
You have enthusiasm for biomolecular and cellular sciences and interest in laboratory-based research. A good command of English is mandatory, as you will be working in an international team. Previous experience with Western blot, flow cytometry, or microscopy is highly advantageous but not mandatory.
Disabled applicants will be considered preferentially in case of equivalent qualifications.
Stay informed by our group website:
https://www.platelets.eu/biomed/nieswandt/
If you are interested, please contact:
stefano.navarro@uni-wuerzburg.de
