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Deutsch Intern
Rudolf Virchow Center for Integrative and Translational Bioimaging

Job Offers

The following positions are currently available at the Rudolf Virchow Center:

Science

A PhD Position on "Structural and biochemical characterization of inhibitory postsynaptic specializations" is available in the group of Prof. Dr. Schindelin

Neurotransmitter receptors are anchored to the cytoskeleton with the aid of scaffolding proteins. At inhibitory synpases the protein gephyrin acts as central scaffolding component by bridging glycine and GABAA receptors and cytoskeletal elements. The Schindelin Iab is interested in gephyrin (Maric et al., Nature Comm. 5, 5767 (2014), Kasaragod et al., Neuron 101, 673-689 (2019)) and other aspects of inhibitory synapse formation and modulation (Soykan et al., EMBO J. 33, 2113-2133 (2014), Kasaragod et al., PNAS USA, E-pub ahead of print (2020)).

Highly motivated candidates with a Masters (or equivalent) degree in biochemistry, molecular biology, biophysics or chemistry, and a keen interest in structural biology, biochemistry, and biophysics are strongly encouraged to apply. Successful applicants must be able to work independently and as part of an international team. Previous experience in one of the following areas, structural biology, biochemistry or biophysics, is required.

lnterested candidates should E-mail an application including a cover Ietter detailing their interests and expertise, their CV, transcripts, and the contact information of at least two references. The PhD students will be part of the Graduate School of Life Sciences. Salary will be according to the collective bargaining agreement (TV-L, 0.65 x E13). Disabled applicants will be preferentially considered in case of equivalent qualifications.

For further information and to apply please contact:

Prof. Dr. Hermann Schindelin
Rudolf-Virchow-Zentrum – Center for Integrative and Translational Bioimaging
Universität Würzburg
Josef-Schneider-Str. 2 I Haus 015
D-97080 Würzburg
Germany
https://www.uni-wuerzburg.de/rvz/forschung/forschungsgruppen/ag-schindelin/
E-mail: teresa.frank@virchow.uni-wuerzburg.de

Please submit your application as a single pdf file by E-mail until March 1st, 2021.

2 PhD Positions (f/m/d) investigating the

“The functional and molecular architecture of the CAK complex” are available in the group of Prof. Dr. Kisker

The general transcription factor II H (TFIIH) plays a central role in both RNA Polymerase II (RNA Pol II) dependent transcription and nucleotide excision repair (NER). The CDK7, MAT1, and CyclinH subunits constitute the cylin-activated kinase (CAK) module, a kinase complex that is crucially involved in promoter clearance, proximal pausing, co-transcriptional chromatin modification, and termination and thus essential to RNA Pol II based transcription. For reference see Peissert et al., PNAS 2020.

Highly motivated candidates with a Masters (or equivalent) degree in biochemistry, molecular biology, biophysics or chemistry and a keen interest in structural biology, biochemistry, and biophysics are strongly encouraged to apply. The positions can be filled as soon as possible. Successful applicants should be able to work independently and as part of an international team. Previous experience in one of the following areas, structural biology, biochemistry or biophysics, is required.

Interested candidates should E-mail an application including a cover letter detailing their interests and expertise, their CV, transcripts, and the contact information of at least two references. The position holders will be part of the Graduate School of Life Sciences. Salary will be according to the collective bargaining agreement (TV-L, 65%). Disabled applicants will be preferentially considered in case of equivalent qualifications.

For further information and to apply please contact:

Prof. Dr. Caroline Kisker
Rudolf-Virchow-Zentrum -Center for Integrative and Translational Bioimaging at the University of Würzburg
Josef-Schneider-St. 2 / Haus D15
D-97080 Würzburg
Germany

E-mail: teresa.frank@virchow.uni-wuerzburg.de

Homepage: https://www.uni-wuerzburg.de/rvz/lehrstuehle/lehrstuhl-fuer-strukturbiologie/

Please submit your application as a single pdf file by February 15th 2021.