Publications
Azido-Ceramides, a Tool to Analyse SARS-CoV-2 Replication and Inhibition—SARS-CoV-2 Is Inhibited by Ceramides
Azido-Ceramides, a Tool to Analyse SARS-CoV-2 Replication and Inhibition—SARS-CoV-2 Is Inhibited by Ceramides
D. Brenner, N. Geiger, J. Schlegel, V. Diesendorf, L. Kersting, J. Fink, L. Stelz, S. Schneider-Schaulies, M. Sauer, J. Bodem, J. Seibel
Int. J. Mol. Sci. 2023, 24(8), 7281
first published: 14 April 2023
Bioorthogonal azido-S1P works as substrate for S1PR1
Bioorthogonal azido-S1P works as substrate for S1PR1
C. Sternstein, J. Schlegel, M. Sauer, J. Seibel
J. Lipid Res. 2023, Vol. 64, Issue 1, 100311, January 01, 2023
first published: 10 November 2022
Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.
Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.
F. Hashemi Arani, S. Kadow, M. Kramer, S. Keitsch, L. Kirchhoff, F. Schumacher, B. Kleuser, P.-M- Rath, E. Gulbins, A. Carpinteiro
Int. J. Mol. Sci. 2022, 23(24), 15510
published: 7 December 2022
Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
D. Péricat, S. Adonai Leon-Icaza, M. Sanchez Rico, C. Mühle, I. Zoicas, F. Schumacher, R. Planès, R. Mazars, G. Gros, A. Carpinteiro, K. A. Becker, J. Izopet, N. Strub-Wourgaft, P. Sjö, O. Neyrolles, B. Kleuser, F. Limosin, E. Gulbins, J. Kornhuber, E. Meunier, N. Hoertel, C. Cougoule
Int. J. Mol. Sci. 2022, 23(21), 13623
published: 7 November 2022
The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis
A. Günther, M. Hose, H. Abberger, F. Schumacher, Y. Veith, B. Kleuser, K. Matuschewski, K. S. Lang, E. Gulbins, J. Buer, A. M. Westendorf, W. Hansen
eLife 2022; 11:e77975.
published: 12 September 2022
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
M. A. Ataide, K. Knöpper, P. Cruz de Casas, M. Ugur, S. Eickhoff, M. Zou, H. Shaikh, A. Trivedi, A. Grafen, T. Yang, I. Prinz, K. Ohlsen, M. Gomez de Aguero, A. Beilhack, J. Huehn, M. Gaya, A.-E. Saliba, G. Gasteiger, W. Kastenmüller
2022 Immunity 55, 1-16
October issue
If you are interested in reading this publication, send us an email to grk2581@uni-wuerzburg.de
The Acid Ceramidase Is a SARS-CoV-2 Host Factor
The Acid Ceramidase Is a SARS-CoV-2 Host Factor
N. Geiger; L. Kersting.; J. Schlegel; L. Stelz; S. Fähr; V. Diesendorf; V. Roll; M. Sostmann; E.-M. König; S. Reinhard; D. Brenner; S. Schneider-Schaulies; M. Sauer; J. Seibel; J. Bodem
Cells 2022, 11, 2532.
published: 15 August 2022
Synthesis and Characterization of Ceramide-Containing Liposomes as Membrane Models for Different T Cell Subpopulations
Synthesis and Characterization of Ceramide-Containing Liposomes as Membrane Models for Different T Cell Subpopulations
S. Eder, C. Hollmann, P. Mandasari, P. Wittmann, F. Schumacher, B. Kleuser, J. Fink, J. Seibel, J. Schneider-Schaulies, C. Stigloher, N. Beyersdorf, S. Dembski
J. Funct. Biomater. 2022, 13(3), 111
published: 2 August 2022
A Comprehensive Review on the Interplay between Neisseria spp. and Host Sphingolipid Metabolites
A Comprehensive Review on the Interplay between Neisseria spp. and Host Sphingolipid Metabolites
S. Peters, I. Fohmann, T. Rudel, A. Schubert-Unkmeir
Cells 2021, 10, 3201
published: 17 November 2021
The Manifold Roles of Sphingolipids in Viral Infections
The Manifold Roles of Sphingolipids in Viral Infections
E. Avota , J. Bodem , J. Chithelen , P. Mandasari , N. Beyersdorf and J. Schneider-Schaulies
Front. Physiol.
published: 29 September 2021
Sphingolipids: Effectors and Achilles Heals in Viral Infections?
Sphingolipids: Effectors and Achilles Heals in Viral Infections?
S. Schneider-Schaulies, F. Schumacher, D. Wigger, M. Schöl, T. Waghmare, J. Schlegel, J. Seibel and B. Kleuser
Cells 2021, 10(9), 2175
published: 24 August 2021
Staphylococcus aureus a-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line
Staphylococcus aureus a-Toxin Induces Acid Sphingomyelinase Release From a Human Endothelial Cell Line
D. Krones, M. Rühling, K. A. Becker, T. C. Kunz, C. Sehl, K. Paprotka, E. Gulbins, M. Fraunholz
Front. Microbiol.
published: 29 July 2021
Editorial: Sphingolipids in Infection Control
Editorial: Sphingolipids in Infection Control
J. Seibel, S. Schneider-Schaulies, B. Kleuser
Front. Cell Dev. Biol.
published: 21 June 2021
Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins
Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins
A. Siegmund, M. A. Afzal, F. Tetzlaff, D. Keinhörster, F. Gratani, K. Paprotka, M. Westermann, S. Nietzsche, C. Wolz, M. Fraunholz, C. A. Hübner, B. Löffler, L. Tuchscherr
Virulence, Volume 12, 2021, Issue 1
published: 12 April 2021
Inhibition of acid sphingomyelinase increases regulatory T cells in humans
Inhibition of acid sphingomyelinase increases regulatory T cells in humans
T. Wiese, F. Dennstädt, C. Hollmann, S. Stonawski, C. Wurst, J. Fink, E. Gorte, P. Mandasari, K. Domschke, L. Hommers, B. Vanhove, F. Schumacher, B. Kleuser, J. Seibel, J. Rohr, M. Buttmann, A. Menke, J. Schneider-Schaulies, N. Beyersdorf
Brain Communications, Volume 3, Issue 2, 2021
published: 5 March 2021
The Expandables: Cracking the Staphylococcal Cell Wall for Expansion Microscopy
The Expandables: Cracking the Staphylococcal Cell Wall for Expansion Microscopy
T. Kunz, M. Rühling, A. Moldovan, K. Paprotka, V. Kozjak-Pavlovic, T. Rudel, M. Fraunholz
Front. Cell. Infect. Microbiol. 11:644750
published: 16 March 2021
Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria
Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria
S. Peters, L. Kaiser, J. Fink, F. Schumacher, V. Perschin, J. Schlegel, M. Sauer, C. Stigloher, B. Kleuser, J. Seibel and A. Schubert-Unkmeir
Scientific Reports 2021, 11, 4300
published: 22nd February 2021
Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis
Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis
J. Fink, F. Schumacher, J. Schlegel, P. Stenzel, D. Wigger, M. Sauer, B. Kleuser and J. Seibel
Org. Biomol. Chem., 2021
published: January 2021
Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy
Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy
R. Götz, T. C. Kunz, J. Fink, F. Solger, J. Schlegel, J. Seibel, V. Kozjak-Pavlovic, T- Rudel, M. Sauer
Nature Communications
published: 2nd December 2020
Modulation of Host Cell Death and Lysis Are Required for the Release of Simkania negevensis
Modulation of Host Cell Death and Lysis Are Required for the Release of Simkania negevensis
R.-D. Koch, E.-M. Hörner, N. Münch, E. Maier, V. Kozjak-Pavlovic
Front. Cell. Infect. Microbiol.
published: 29 October 2020
Detection of Functionalized Sphingolipid Analogs in Detergent-Resistant Membranes of Immune Cells
Detection of Functionalized Sphingolipid Analogs in Detergent-Resistant Membranes of Immune Cells
Fink J., Seibel J., Avota E.
Bieberich E. (eds) Lipid Rafts. Methods in Molecular Biology, vol 2187. Humana, New York, NY
published: August 2020
High-Yielding Water-Soluble Asymmetric Cyanine Dyes for Labeling Applications
High-Yielding Water-Soluble Asymmetric Cyanine Dyes for Labeling Applications
N. Wolf, L. Kersting, C. Herok, C. Mihm, J. Seibel
J. Org. Chem. 2020, 85, 15, 9751-9760
published: 20 July 2020
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Lang, J., Bohn, P., Bhat, H. et al.
Nat Commun 11, 1338 (2020).
published: March 2020
