Infection Biology, Molecular and Cellular Microbiology
The Rudel lab studies pathogenicity mechanisms of different microorganisms, in particular the manipulation of various signalling cascades and cellular processes such as the cell death pathways in the host. In this context the infection biology of obligate intracellular bacteria such as Chlamydia is one of the major topics. In addition, the contribution of (co-)infections to the onset of ovarian cancer and the signaling pathways involved as well as the analysis of the interaction of pathogenic microorganisms with mitochondria are subject of research efforts. In the context of the GRK 2234, we are studying the role of chlamydial deubiquitylating enzymes during infection.