English Intern
    MSc Life Sciences

    Publications by FOKUS students

    The program only started in the winter semester 2012/2013. Currently (Jan 2020), of the 51 students who started into the program ever since, 27 have begun or already finished a doctoral project at JMU, others left to continue in other places. Of those who started here, 19 have already published.

    Species Specific Differences of CD1d Oligomer Loading In Vitro
    Paletta D, Fichtner AS, Starick L, Porcelli SA, Savage PB, Herrmann T.
    PLoS One. 2015 Nov 24;10(11)

    Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus)
    Fichtner AS, Paletta D, Starick L, Schumann RF, Niewiesk S, Herrmann T.
    Immunology. 2015 Dec;146(4):618-629

    The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d-glycolipid binding of iNKT TCRs
    Paletta D, Fichtner AS, Hahn AM, Starick L, Beyersdorf N, Monzon-Casanova E, Mueller TD, Herrmann T.
    Eur J Immunol. 2015 Jul;45(7):2122-33

    Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice
    Anita Masic, Ana Maria Valencia Hernandez, Sudipta Hazra, Jan Glaser, Ulrike Holzgrabe, Banasri Hazra, Uta Schurigt
    PLOS one, November 10, 2015

    Draft Genome Sequence of the Moderately Heat-Tolerant Lactococcu lactis subsp. lactis bv. diacetylactis Strain GL2 from Algerian Dromedary Milks
    Gabed N, Yang M, Bey Baba Hamed M, Drici H, Gross R, Dandekar T, Liang C.
    Genome Announc. 2015 Nov 19;3(6)

    Whole transcriptome profiling reveals the RNA content of motor axons
    Briese M, Saal L, Appenzeller S, Moradi M, Baluapuri A, Sendtner M.
    Nucleic Acids Res. 2016 Feb 29;44(4):e33

    A Candida albicans regulator of disseminated infection operates primarily as a repressor and governs cell surface remodeling
    Böhm L, Muralidhara P, Pérez JC.
    Mol Microbiol. 2016 Apr;100(2):328-44

    Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology
    Candemir E, Kollert L, Weißflog L, Geis M, Müller A, Post AM, O׳Leary A, Harro J, Reif A, Freudenberg F.
    Eur Neuropsychopharmacol. 2016 Apr;26(4):741-755

    Different promoter affinities account for specificity in MYC-dependent gene regulation
    Lorenzin F, Benary U, Baluapuri A, Walz S, Jung LA, von Eyss B, Kisker C, Wolf J, Eilers M, Wolf E.
    Elife. 2016 Jul 27;5

    High GDF-15 Serum Levels Independently Correlate with Poorer Overall Survival of Patients with Tumor-Free Stage III and Unresectable Stage IV Melanoma
    Weide B, Schäfer T, Martens A, Kuzkina A, Uder L, Noor S, Garbe C, Harter PN, Mittelbronn M, Wischhusen J.
    J Invest Dermatol. 2016 Dec;136(12):2444-2452

    The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth
    Weiste C, Pedrotti L, Selvanayagam J, Muralidhara P, Fröschel C, Novák O, Ljung K, Hanson J, Dröge-Laser W.
    PLoS Genet. 2017 Feb 3;13(2): eCollection 2017 Feb.

    Additive manufacturing of polymer melts for implantable medical devices and scaffolds
    Youssef A, Hollister SJ, Dalton PD.
    Biofabrication. 2017 Feb 28;9(1):012002; Review

    Abrogation of Gap Junctional Communication in ES Cells Results in a Disruption of Primitive Endoderm Formation in Embryoid Bodies
    Wörsdörfer P, Bosen F, Gebhardt M, Russ N, Zimmermann K, Komla Kessie D, Sekaran T, Egert A, Ergün S, Schorle H, Pfeifer A, Edenhofer F, Willecke K.
    Stem Cells. 2017 Apr;35(4):859-871

    Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single-use bioreactors
    Kwok CK, Ueda Y, Kadari A, Günther K, Heron A, Schnitzler AC, Rook M, Edenhofer F. J
    Tissue Eng Regen Med. 2017 Apr 6

    Dissection of mechano response elements in promoter sites of the mechanoresponsive CYR61 gene
    Seefried L, Müller-Deubert S, Krug M, Youssef A, Schütze N, Ignatius A, Jakob F, Ebert R.
    Exp Cell Res. 2017 May 15;354(2):103-111

    The Snf1-activating kinase Sak1 is a key regulator of metabolic adaptation and in vivo fitness of Candida albicans
    Ramírez-Zavala B, Mottola A, Haubenreißer J, Schneider S, Allert S, Brunke S, Ohlsen K, Hube B, Morschhäuser
    J. Mol Microbiol. 2017 Jun;104(6):989-1007

    Neurobiology of local and intercellular BDNF signaling
    Sasi M, Vignoli B, Canossa M, Blum R.
    Pflugers Arch. 2017 Jun; 469(5-6):593-610.Mar 9. Review. Erratum in: Pflugers Arch. 2017 Jun;469(5-6):611

    The Snf1-activating kinase Sak1 is a key Regulator oF metabolic adaptation and in vivo fitness of Candida albicans
    Ramírez-Zavala B, Mottola A, Haubenreißer J, Schneider S, Allert S, Brunke S, Ohlsen K, Hube B, Morschhäuser
    J. Mol Microbiol. 2017 Jun;104(6):989-1007

    Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain
    Forero A, Rivero O, Wäldchen S, Ku HP, Kiser DP, Gärtner Y, Pennington LS, Waider J, Gaspar P, Jansch C, Edenhofer F, Resink TJ, Blum R, Sauer M, Lesch KP.
    Front Cell Neurosci. 2017 Sep 26;11:307

    PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters
    Gerlach JM, Furrer M, Gallant M, Birkel D, Baluapuri A, Wolf E, Gallant P.
    Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9224-E9232.

    Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle
    Büchel G, Carstensen A, Mak KY, Roeschert I, Leen E, Sumara O, Hofstetter J, Herold S, Kalb J, Baluapuri A, Poon E, Kwok C, Chesler L, Maric HM, Rickman DS, Wolf E, Bayliss R, Walz S, Eilers M.
    Cell Rep. 2017 Dec 19;21(12):3483-3497

    The Armadillo (Dasypus novemcinctus): A Witness but Not a Functional Example for the Emergence of the Butyrophilin 3/Vγ9Vδ2 System in Placental Mammals
    Fichtner AS, Karunakaran MM, Starick L, Truman RW, Herrmann T.
    Front Immunol. 2018 Feb 23;9:265

    Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation
    Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C, Pluchino S.
    Cell Stem Cell. 2018 Mar 1;22(3):355-368

    An open source tool for automatic spatiotemporal assessment of calcium transients and local 'signal-close-to-noise' activity in calcium imaging data
    Prada J, Sasi M, Martin C, Jablonka S, Dandekar T, Blum R.
    PLoS Comput Biol. 2018 Mar 30;14(3):e1006054

    Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3
    Jansch C, Günther K, Waider J, Ziegler GC, Forero A, Kollert S, Svirin E, Pühringer D, Kwok CK, Ullmann R, Maierhofer A, Flunkert J, Haaf T, Edenhofer F, Lesch KP.
    Stem Cell Res. 2018 Apr;28:136-140

    Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation
    Milanos S, Kuenzel K, Gilbert DF, Janzen D, Sasi M, Buettner A, Frimurer TM, Villmann C.
    Biol Chem. 2018 May 24;399(6):549-563

    C. elegans Blastomeres Clear the Corpse of the Second Polar Body by LC3-Associated Phagocytosis.
    Fazeli G, Stetter M, Lisack JN, Wehman AM.
    Cell Rep
    . 2018 May 15;23(7):2070-2082. doi: 10.1016/j.celrep.2018.04.043.

    Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice
    Yuan X, Klein D, Kerscher S, West BL, Weis J, Katona I, Martini R.
    J Neurosci. 2018 May 9;38(19):4610-4620

    Dimension-Based Design of Melt Electrowritten Scaffolds
    Hrynevich A, Elçi BŞ, Haigh JN, McMaster R, Youssef A, Blum C, Blunk T, Hochleitner G, Groll J, Dalton PD.
    Small. 2018 May;14(22):e1800232

    The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ
    Bury S, Soundararajan M, Bharti R, von Bünau R, Förstner KU, Oelschlaeger TA.
    Front Microbiol. 2018 May 29;9:929

    Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene
    Klein T, Günther K, Kwok CK, Edenhofer F, Üçeyler N.
    Stem Cell Res. 2018 Aug;31:222-226

    Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells
    Mekala SR, Wörsdörfer P, Bauer J, Stoll O, Wagner N, Reeh L, Loew K, Eckner G, Kwok CK, Wischmeyer E, Dickinson ME, Schulze H, Stegner D, Benndorf RA, Edenhofer F, Pfeiffer V, Kuerten S, Frantz S, Ergün S.
    Circ Res. 2018 Aug 31;123(6):686-699

    Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration
    Shashi Shashi V, Magiera MM, Klein D, Zaki M, Schoch K, Rudnik-Schöneborn S, Norman A, Lopes Abath Neto O, Dusl M, Yuan X, Bartesaghi L, De Marco P, Alfares AA, Marom R, Arold ST, Guzmán-Vega FJ, Pena LD, Smith EC, Steinlin M, Babiker MO, Mohassel P, Foley AR, Donkervoort S, Kaur R, Ghosh PS, Stanley V, Musaev D, Nava C, Mignot C, Keren B, Scala M, Tassano E, Picco P, Doneda P, Fiorillo C, Issa MY, Alassiri A, Alahmad A, Gerard A, Liu P, Yang Y, Ertl-Wagner B, Kranz PG, Wentzensen IM, Stucka R, Stong N, Allen AS, Goldstein DB; Undiagnosed Diseases Network, Schoser B, Rösler KM, Alfadhel M, Capra V, Chrast R, Strom TM, Kamsteeg EJ, Bönnemann CG, Gleeson JG, Martini R, Janke C, Senderek, J.
    EMBO J. 2018 Dec 3;37(23). pii: e100540

    Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory and autonomic neuropathy type 5
    Klein T, Henkel L, Klug K, Kwok CK, Klopocki E, Üçeyler N.
    Stem Cell Res. 2018 Dec;33:171-174

    The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
    Westermann AJ, Venturini E, Sellin ME, Förstner KU, Hardt WD, Vogel J.
    MBio. 2019 Jan 2;10(1). pii: e02504-18

    Heterozygous Tbk1 loss has opposing effects in early and late stages of ALS in mice.
    Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, Sendtner M, Ludolph AC, Danzer KM, Lobsiger CS, Freischmidt A, Weishaupt JH.
    J Exp Med. 2019 Feb 4;216(2):267-278. doi: 10.1084/jem.20180729.


    Medical-grade polycaprolactone scaffolds made by melt electrospinning writing for oral bone regeneration - a pilot study in vitro.
    Fuchs A, Youssef A, Seher A, Hochleitner G, Dalton PD, Hartmann S, Brands RC, Müller-Richter UDA, Linz C.
    BMC Oral Health. 2019 Feb 1;19(1):28. doi: 10.1186/s12903-019-0717-5.

    Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy.
    Klein T, Klug K, Henkel L, Kwok CK, Edenhofer F, Klopocki E, Kurth I, Üçeyler N.
    Stem Cell Res. 2019 Mar;35:101396. doi: 10.1016/j.scr.2019.101396

    Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.
    Herold S, Kalb J, Büchel G, Ade CP, Baluapuri A, Xu J, Koster J, Solvie D, Carstensen A, Klotz C, Rodewald S, Schülein-Völk C, Dobbelstein M, Wolf E, Molenaar J, Versteeg R, Walz S, Eilers M.
    Nature. 2019 Mar;567(7749):545-549. doi: 10.1038/s41586-019-1030-9.

    A new multilayered membrane for tissue engineering of oral hard- and soft tissue by means of melt electrospinning writing and film casting - An in vitro study.
    Fuchs A, Youssef A, Seher A, Hartmann S, Brands RC, Müller-Richter UDA, Kübler AC, Linz C.
    J Craniomaxillofac Surg. 2019 Apr;47(4):695-703. doi: 10.1016/j.jcms.2019.01.043.

    MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.
    Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang SY, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E.
    Mol Cell. 2019 May 16;74(4):674-687.e11. doi: 10.1016/j.molcel.2019.02.031.

    The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes.
    Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S.
    Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071

    The Impact of Melt Electrowritten Scaffold Design on Porosity Determined by X-Ray Microtomography.
    Youssef A, Hrynevich A, Fladeland L, Balles A, Groll J, Dalton PD, Zabler S.
    Tissue Eng Part C Methods. 2019 Jun;25(6):367-379. doi: 10.1089/ten.TEC.2018.0373.

    An Intragenic Recombination Event Generates a Snf4-Independent Form of the Essential Protein Kinase Snf1 in Candida albicans.
    Mottola A, Morschhäuser J.
    mSphere. 2019 Jun 19;4(3). pii: e00352-19. doi: 10.1128/mSphere.00352-19.
    The aggregation state of α-synuclein deposits in dermal nerve fibers of patients with Parkinson's disease resembles that in the brain. Kuzkina A, Schulmeyer L, Monoranu CM, Volkmann J, Sommer C, Doppler K. Parkinsonism Relat Disord. 2019 Jul;64:66-72. doi: 10.1016/j.parkreldis.2019.03.003.
    Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility.
    Donadio V, Doppler K, Incensi A, Kuzkina A, Janzen A, Mayer G, Volkmann J, Rizzo G, Antelmi E, Plazzi G, Sommer C, Liguori R, Oertel WH. Eur J Neurol. 2019 Oct;26(10):1245-1251. doi: 10.1111/ene.13939.
    Comprehensive Flux Modeling of Chlamydia trachomatis Proteome and qRT-PCR Data Indicate Biphasic Metabolic Differences Between Elementary Bodies and Reticulate Bodies During Infection.
    Yang M, Rajeeve K, Rudel T, Dandekar T.
    Front Microbiol. 2019 Oct 15;10:2350. doi: 10.3389/fmicb.2019.02350
    Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells. Wörsdörfer P, Dalda N, Kern A, Krüger S, Wagner N, Kwok CK, Henke E, Ergün S.
    Sci Rep. 2019 Oct 30;9(1):15663. doi: 10.1038/s41598-019-52204-7.

    A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
    Schmidt S, Gay D, Uthe FW, Denk S, Paauwe M, Matthes N, Diefenbacher ME, Bryson S, Warrander FC, Erhard F, Ade CP, Baluapuri A, Walz S, Jackstadt R, Ford C, Vlachogiannis G, Valeri N, Otto C, Schülein-Völk C, Maurus K, Schmitz W, Knight JRP, Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A.
    Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0.

    K5 Capsule and Lipopolysaccharide Are Important in Resistance to T4 Phage Attack in Probiotic E. coli Strain Nissle 1917. Soundararajan M, von Bünau R, Oelschlaeger TA.
    Front Microbiol. 2019 Nov 29;10:2783. doi: 10.3389/fmicb.2019.02783.