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    Rudolf-Virchow-Zentrum für Experimentelle Biomedizin

    RVZ Gastvortrag: Dr. Silvia von Karstedt

    "Redox pathway plasticity allows ferroptosis escape of small cell lung cancer"
    Datum: 04.06.2020, 17:00 - 18:00 Uhr
    Ort: Medizin, Geb. D15, 1.002-004
    Veranstalter: Rudolf-Virchow-Zentrum
    Vortragende*r: Dr. Silvia von Karstedt
    www.cecad.uni-koeln.de

    Dr. Silvia von Karstedt vom CECAD Research Center (Köln) wird am RVZ einen Gastvortrag halten.

    "In addition to direct ligand/receptor interaction-triggered regulated cell death such as extrinsic apoptosis and necroptosis, cancer cells can also undergo selective pressure from oxidative damage-associated regulated cells death such as ferroptosis, evasion of which is selected for in lung cancers. To identify actionable vulnerabilities in these selection processes, the von Karstedt lab investigates the function of different modes of cell death in a) the selection of the fittest mutant KRAS clone in non-small cell lung cancer (NSCLC) and early pancreatic cancer formation and b) in comparison these selection mechanisms in never-KRAS-mutated small cell lung cancer (SCLC)."

    Mehr Details über ihre Forschung hier.

    Eingeladen von  Dr. José Pedro Friedmann Angeli

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