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Rudolf Virchow Center for Experimental Biomedicine

Bachelor's/Master's Thesis

If capacities are free, projects for Bachelor and Master theses can be offered. However, this is at the discretion of the respective reasearch group. Please inform yourself about the scientific priorities of the individual research groups and contact the research group leader directly by email.

The following positions are currently available:

The Rudolf Virchow Center / Research Center for Experimental Biomedicine of the University of Würzburg is currently searching for a highly motivated

Bachelor/ Master student (f/m/d)
(Biology / Biomedicine / Biophysics)

Mirror-enhanced FCCS (meFCCS) in the field of time resolved spectroscopy on live cells

In a cross-disciplinary approach we combine the concepts of fluorescence time resolved spectroscopy with tricks from material sciences.

The project involves optimization of the conditions to boosting the molecular brightness for dual color fluorescence cross correlation spectroscopy (FCCS) on nanocoated coverslips. The main goal is to uncover the fast dynamics of GPCRs in live cells with FRET-FCCS method, which required high molecular brightness. Our lab has already established the protocol for better molecular brightness with single color lipid bilayers in metal coated coverslips. In further extension of the work we need to establish this for two color biomimetic systems and also in live cells. The project particularly requires enthusiasm for biomolecular sciences and confocal microscopy. Good knowledge of the English language is a prerequisite. Previous experience with cell culture and/or advanced microscopic techniques is highly advantageous but not mandatory.

Please contact: katrin.heinze@virchow.uni-wuerzburg.de

Prof. Dr. Katrin Heinze, RVZ, Josef-Schneider-Str. 2 / Haus D15, 97080 Würzburg